A Study on the Shift-Based Production Scheduling Problem from Active Pharmaceutical Ingredients Manufacturing Process
碩士 === 國立成功大學 === 製造資訊與系統研究所 === 103 === The Active Pharmaceutical Ingredients industry is developed rapidly these years. Because of the various products with low volume, the Active Pharmaceutical Ingredients use the same equipment with different process route to produce various products, the demand...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2014
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| Online Access: | http://ndltd.ncl.edu.tw/handle/51646159319252057713 |
| Summary: | 碩士 === 國立成功大學 === 製造資訊與系統研究所 === 103 === The Active Pharmaceutical Ingredients industry is developed rapidly these years. Because of the various products with low volume, the Active Pharmaceutical Ingredients use the same equipment with different process route to produce various products, the demand of manpower fluctuates in the same equipment. And sometimes the operators can operate more than one equipment at the same time. In addition, there is some restriction due to the specialty and chemical reaction which makes company have difficulty in controlling the production process in detailing arrangement and efficiency. This study use the Value Stream Map（VSM）and Standardized Work Combination Table in Toyota Production System（TPS） that be the base of research. And consider the chemical reaction restriction in the scheduling. The main method is considering the critical resource use the Theory of Constraints（TOC） conception that simulation can scheduling based on the state of processing batch. Comparing the simulation of real production with the scheduling scenario, it can even decrease of makespan 2-8% in different scenario. According to the result, Using scheduling in Active Pharmaceutical Ingredients shifted-based production can decrease the delay of delivery and production cost.
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