Surface Characteristics and Biological Evaluation of Titanium Dental Implants Modified by the Combination of SLA-like and Alkali-treated Techniques

• Main Authors: Hsing-Chien Lee, 李幸謙
• Other Authors: Hui-Ping Feng
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/ecb7hf

碩士 === 明志科技大學 === 機械工程系機械與機電工程碩士班 === 103 === The study employed an SLA-like treatment incorporated with the alkali treatment with 5M NaOH for few hours to obtain sodium titanate thin film which was superimposed onto the SLA-like-treated titanium surface. This new compound surface modification technology could lead to both merits because of not only micron and sub-micron structure surface topography by the SLA-like-treatment favoring osseointegration and long-term stability but also the sodium titanate thin film by the alkali treatment inducing bone-like apatite formation to enhance bone growth for titanium implants. First, in this study, titanium disks were blasted with large grits and followed by acid-etching to nearly get the same surface topography as commercially available SLA dental implants, with micron and sub-micron pits on the surface. Further, the SLA-like surface was processed with the alkali treatment with 5M NaOH for 15, 30, and 45 minutes. Scanning electron microscopy showed that sodium titanate nano-scale thin films with nano pore structure were deposited onto the SLA-like surface. Contact angle test indicated that surface hydrophilicity was remarkably enhanced. Next, both specimens of the compound surface treatment and the single SLA-like treatment were immersed in SBF for 14 days. The ICP test showed that the calcium ion concentration of the SLA-like specimens did not change significantly while reached the minimum value for the compound surface treatment for 7 days. It was obvious that the SLA-like specimens with the sodium titanate nano-scale thin film by the alkali treatment could induce calcium ions deposition onto the surfaces to form the bone-like apatite in the SBF for the short time. Finally, the study conducted cell viability and toxicity tests. Comparing to the specimens through the single SLA-like treatment, the biocompatibility of the compound surface modification treatment disks displayed better. This preliminary study has nearly succeeded in developing a new promising compound surface treatment technology for titanium dental implants.