| Summary: | 碩士 === 輔仁大學 === 營養科學系碩士班 === 104 === Introduction: Eating betel nuts, smoking and drinking were the majority of carcinogenic factors so that oral cancer occurred mostly in men in Taiwan. Patients had a high weight loss and lower quality of life because of tumor location, cancer stage, treatment toxicity and side effects. Study suggested that nutrition intervention should be administered before the start of cancer therapy. In Taiwan, 30% adults had a deficiency of vitamin B2, so the status of vitamin B2 would be monitored in those patients.
Objectives: The aim of the study was to improve the nutritional status of patients with oral cancer and reduce the percentages of body weight loss through personalized nutrition counseling.
Design: This was a random, control trail. We randomly assigned 60 patients within 20-70 years old with postoperative oral cancer receiving concurrent chemoradiotherapy (CCRT) into two groups. Treatment group (T group) (n=30) had personalized nutrition counseling (1 time/week) until 1 month after treatment and control group (C group) (n=30) only got one nutritional education manual and was taken care by CGMF during treatment. The nutritional status would be assessed by Patient-Generated Subjective Global Assessment (PG-SGA), body composition, blood biochemical, physical activities questionnaire and 24-hour food intake at 4 timings: before treatment (T0), ending treatment (T1), treatment after 1 month (T2) and 3 months (T3) in two group. The side effects and compliance were also be observed.
Results: No significant difference in baseline was observed between groups. There was no significant different in body weight loss and dietary intake between C group and T group during the period of time. However, vitamin D intake was higher than C group. No significant differences in PG-SGA, blood biochemical and vitamin B2 were observed between groups at 4 timings.
Conclusion: The effect of personal nutritional counseling in patients with oral cancer improves dietary intake after CCRT. Nutritional counseling should be given after CCRT.
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