A Study of Applying Survival Analysis to the National Health Insurance Research Database to Analyze Different Antiplatelet Therapy After CABG Surgery

• Main Authors: Yi-Shiang Tzeng, 曾奕翔
• Other Authors: Ben-Chang Shia
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/17603158283763384199

碩士 === 輔仁大學 === 統計資訊學系應用統計碩士班 === 103 === When either drug therapy or PCI/PTCA can’t cure Coronary Artery Disease (CAD), the Coronary Artery Bypass Graft (CABG) is the best treatment of CAD. However, Although CABG can improve the symptom of CAD, there has some risk of complications after CABG. The American College of Cardiology/American Heart Association (ACC/AHA) had announce that the therapy after CABG would reduce the occur of complications.The study wonder to discuss the prognosis of CABG under the different therapy, and find out the prognosis factors which significance infect the risk of death. The study object are patients who had the first CABG in NHIRD from 2000 to 2009. The patients would separate Aspirin, Clopidogrel, Aspirin plus Clopidogrel by therapy.To discuss the differents of Ischemic, Venous Thromboembolism, Bleeding, death, 30-day readmission, 30-day PCI/CABG under the therapy by Chi-Square; and to discuss a composite of three different drugs to prognostic indicators of survival outcome survival, survival time and the relative risks by Kaplan-Meier Curve、Log-Rank Test、Gehan-Breslow Test and Cox Proportional Hazards Model. And find out prognosis factors by the Cox Proportional Hazards. The research result showed that thers has significant diffterent in Ischemic, Venous Thromboembolism, 30-day readmission underthe three group. The survival and survival time which has the best. Age, the level of Comorbidity, vascular, hospitalization days and 30-day readmission are the prognosis factors of death.