The associations between vegetarian diet and the levels of blood sugar, lipid profiles, oxidative stress, and inflammation status in patients with type 2 diabetes mellitus

• Main Authors: Ming-Yang Wang, 王明揚
• Other Authors: 林娉婷
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/14762159199672231582

碩士 === 中山醫學大學 === 營養學系碩士班 === 103 === Almanac of food consumption survey in Taiwan indicates that 10 % of the populations are vegetarians. The purpose of this study was to examine the correlations between the levels of blood glucose, lipid profiles, oxidative stress, and inflammatory makers in vegetarians and omnivores who had type 2 diabetes. We recruited 54 vegetarians and 100 omnivores had type 2 diabetes. The characteristics of subjects (ie. gender、age、24-hours dietary recall, and lifestyle habits) were collected and anthropometry, blood pressure, fasting glucose, hemoglobin A1c, lipid profile (total cholesterol, triglyceride、apolipoprotein-A1 and apolipoprotein-B), oxidative stress markers (malondialdehyde and oxidized low-density lipoprotein), antioxidant enzymes activities (superoxide dismutase、catalase and glutathione peroxidase), and inflammatory markers (high-sensitivity C-reactive protein and high-sensitivity interleukin-6) were measured. The results showed that vegetarians had higher values for ratios of polyunsaturated fatty acid to saturated fatty acid intake, ratios of monounsaturated fatty acid to saturated fatty acid intake, serum triglyceride, oxidative stress, and inflammatory makers than omnivores. In addition, the values for ratios of polyunsaturated fatty acid to saturated fatty acid intake and serum triglyceride were significantly positively correlated with the level of oxidative stress, and inflammatory makers were significantly negatively correlated with antioxidant enzymes activities. As a result, we suspected that vegetarians with type 2 diabetes had higher levels of triglyceride and inflammation status might be associated with a higher oxidative stress.