| Summary: | 碩士 === 嘉南藥理大學 === 藥學系 === 103 === According to the ranking of global End-Stage Renal Disease (ESRD) in 2013 from The United States Renal Data System (USRDS), the prevalence of ESRD increased from 2285 to 2584 people per million people. Medicine diversified such as hysician-dispensed, over-the-counter drugs, Chinese herbal medicine, polypharmacy, and inappropriate medication may cause drug-drug interaction and adverse drug reactions (ADR).
A total of 222 subjects who were over twenty years old, recruited from four dialysis centers in a district of Tainan city, Taiwan. Data collection was conducted from 04-28-2015 to 06-06-2015. The study used self-administered questionnaire survey, included subjects that divided into two subgroups by dialysis: dialysis and non-dialysis. Participants were excluded if they had kidney injury. All statistical analyses were performed using SPSS statistical software, version 18.0.
The majority subjects were over 50 years old, and have long-term use of medicines to control diseases included chronic kidney disease, hyperlipidemia , hypertension, diabetes, and cardiovascular disease. The drug category included prescription drugs were 216 people (96.9%), herbal preparations were 25 people (11.2%), dietary supplements were 62 people(27.8%). There were 216 people (96.9 % ) take prescribed drugs: 1-3 species were 58 people (38.1%), 4-6 species were 98 people (43.9%), 7-9 kinds were 31 people (13.9%), and more than 10 kinds were 4 people(1.8%). And 25 people (11.2%) take herbal preparations at the same time, 1-3 species were 24 people (10.8%). And 62 people (27.8%) took dietary supplements at the same time, 1-3 species were 57 people (25.6.8%).The cognition, attitude and behavior of taking drug in dialysis patients was significantly better than non-dialysis patients, possibly because dialysis patients have more experience in care kidney disease. In our study, CKD patients were lack of pharmaceutical service by the pharmacists in terms of medication knowledge and consultation effectiveness. Pharmacists lack of better opportunity and environmental condition in terms of CKD patients in pharmaceutical services.
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