Prognostic Evaluation of Brain Injury Patients by Heart Rate Variability Analysis

• Main Authors: Yi-Cheng Tu, 凃佾呈
• Other Authors: Hsueh-Yi Lu
• Format: Others
• Language: zh-TW
• Published: 2014
• Online Access: http://ndltd.ncl.edu.tw/handle/11173330436981326726

碩士 === 國立雲林科技大學 === 工業工程與管理系 === 102 === Bain injury can be divided into traumatic cranial hemorrhage and spontaneous intracranial hemorrhage. On the other hand, brain tissue damage is caused by brain injury that it often leads to some of serious complications happen. According to the research of brain injury that brain injury may cause autonomic dysfunction. The brain injury will trigger secondary brain injury indirectly and increase the prevalence and mortality. This research combines two areas of heart rate variability analysis and brain injury. The research object is brain injury patients in the ICU. In this study, we obtain and utilize electrocardiography data from the brain injury patients to perform the heart rate variability analysis. We utilize heart rate variability to evaluate the brain injury patients' severity and recovery status within the six months period. Moreover, we observe the relationship between the activity of ANS and clinical condition. The results indicate that a notable reduction of HRV is found in brain injury patients who have a bad prognosis and severe coma. Regarding the HRV indices, the SDNN, VLF, LF, HF and TP were significantly reduced in the subgroup which has a bad prognosis and severe coma. It means that the brain injury patients, who have a bad prognosis and severe coma, are predisposed to have cardiac autonomic dysfunction. HRV is a powerful tool to evaluate the autonomic functions in patients with brain damage of various degrees.