| Summary: | 碩士 === 國立陽明大學 === 生醫光電研究所 === 102 === Urinary Stone is a common disease in Urological system，when people suffering from this disease , doctors will give them treatments . And the recurrent rate of urinary stone is high. However urinary stone formation have large relevance between patient's diet and genetic, so it’s important to know the composition of the stone. If knowing the composition of urinary stone , the doctor would give medicine treatment or diet suggestion that can avoid the risk of operation and reducing the waste of medical expense.
In this research , we use Raman Spectroscopy as a tool to detect urinary stone and crystals . Raman technology have some advantages which would not interfere with the water signal, and its spectral band is narrow, and therefore has a high discrimination , rapid detection of different substances with specific peaks. Therefore, from the peak position in the spectra that can be suitable for use in detection and analysis . If we apply this technology in the hospital , it can offer some objective information to the doctor , .
For now, we have developed an automatic detection system, which combines raman spectroscopy and fluorescent systems. This detection device with magnetic nanoparticles can specific bonded for calcium-based stone or crystals , and label the location of crystals. This technology can reduce the searching time of urine sample . and will help us to know the type of crystal or stone quickly.
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