Synthesis of the α-L-iduronidase substrate and inhibitors

碩士 === 國立臺灣大學 === 化學研究所 === 102 === α-L-iduronidase (IDUA), an endoglycosidase, cleaves the 1,4-glycosidic bond between L-iduronic acids (L-IdoA) and D-glucosamine (or D-galactosamine) in heparin and heparan sulfate. The inhibition study of IDUA is important but rarely mentioned in the literatur...

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Bibliographic Details
Main Authors: Wayne Hsi, 奚偉恩
Other Authors: 羅禮強
Format: Others
Language:en_US
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/f6etyc