A study on association between male lung cancer incidence trends analysis by histologic types and air pollution in Taiwan

• Main Authors: Po-Yin Chang, 張珀銀
• Other Authors: Bingchiang Jeng
• Format: Others
• Language: zh-TW
• Published: 2014
• Online Access: http://ndltd.ncl.edu.tw/handle/06959694144142130856

博士 === 國立中山大學 === 資訊管理學系研究所 === 102 === Background: Although radical shifts in smoking trends over the past few decades, male lung cancer remains a major cause of cancer deaths in many developed countries, and one of the most important public health issues. This study analyzed the recent trends in male lung cancer incidence rates with smoking prevalence in Taiwan (1995-2008) by histological subtypes. Methods: Age-standardized incidence rates were computed using WHO (2000) standard population as reference, where age, period and cohort effects are analyzed by Poisson APC models to see how they affect the trend. Results: Nevertheless smoking prevalence in Taiwan drops since 1976, the male lung cancer incidence rate still increase until 2004, and adenocarcinoma cancer has replaced squamous cell carcinoma as the most common lung cancer subtype. The results suggested that future cancer trends analysis could benefit from the model included potential air pollution factors as PM₁₀, SO₂, and O₃. Contribution: Detail analyses show that the increased incidence cases may not fully explained by the previous studies arguing that Taiwan’s future lung cancer prevention focus should include not only tobacco control but also other possible risk factors as air pollution factors: PM₁₀, SO₂, and O₃.