| Summary: | 碩士 === 國立東華大學 === 電機工程學系 === 102 === Acupuncture is a traditional Chinese medicine method which is used acupoints to cure many diseases. On 1996 WHO announced 64 indications for acupuncture treatment. According to the theory of Chinese medicine , Zusanli (ST-36) is one of the four most important acupoints because it coordinates the functions of the immunological and gastrointestinal systems. But the detailed mechanism of acupuncture is yet not clear and effect of acupuncture also lack scientific evidence. Therefore our research attempted to measure the pulse signal of nailfold microcirculation through non-invasive our invented microcirculation detector.
Our research subjects were 28 healthy young adults (22 males and 6 females). We measured their nailfold peripheral blood flow and autonomic activities by computing the area under the pulse volume curves and Heart Rate Variability (HRV) through photoplethysmography (PPG) and electrocardiography (ECG) before and after acupuncture at Zusanli. Moreover, complexity of physiological signals was compared with multiscale entropy (MSE) and short time MSE (sMSE) before and after acupuncture.
Bland Altman analysis of the perfusion index (PI) showed that the majority of values were located within 1.96 SD. This suggested our data has high consistency and our invented microcirculation detector has high accuracy.The second result demonstrated significant elevation of peripheral blood flow in all 28 subjects during and after acupuncture. On the other hand, significantly reduced sympathetic activities and elevated parasympathetic activities were noted in subjects with body mass index (BMI) <25. It suggested after acupuncture healthy young adults parasympathetic activities elevate. Additionally, MSE analysis of R-R interval (RRI) from 5-minute recording of ECG from subjects with BMI<25 before and after acupuncture showed significantly elevated sMSE immediately after acupuncture. However, no significant difference was noted in MSE between the two time points.
In conclusion, the results of our study demonstrated that acupuncture at Zusanli augments systemic parasympathetic activities and peripheral microcirculation. Furthermore, sMSE revealed increased physiological complexity after acupuncture for individuals of normal healthy weight (BMI <25).
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