The Effects of Different Treatment Model on Achilles’ Tendon Rupture Recovery.

碩士 === 國立東華大學 === 體育與運動科學系 === 102 === Abstract The aim of this study was to investigate the effect of different treatment model on Achilles tendon rupture recovery on different time in rats. Methods: Forty-five Spraque-Dawley (SD) male rats (eight weeks old) randomly assigned to three groups: contr...

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Main Authors: Wun-Yi Fang, 方文怡
Other Authors: Chang-Bin Yang
Format: Others
Published: 2014
Online Access:http://ndltd.ncl.edu.tw/handle/ng465f
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spelling ndltd-TW-102NDHU54190112019-05-15T21:32:18Z http://ndltd.ncl.edu.tw/handle/ng465f The Effects of Different Treatment Model on Achilles’ Tendon Rupture Recovery. 不同處理模式對阿基里斯肌腱斷裂後修復的影響 Wun-Yi Fang 方文怡 碩士 國立東華大學 體育與運動科學系 102 Abstract The aim of this study was to investigate the effect of different treatment model on Achilles tendon rupture recovery on different time in rats. Methods: Forty-five Spraque-Dawley (SD) male rats (eight weeks old) randomly assigned to three groups: control, exercise, immobilization+exercise. Exercise group was exercise intervention at five-day post injury. Immobilization+exercise group was immediately immobilization used cast after injury, and dismantle cast at the same time exercise intervention was began at four-week post injury. The Achilles tendon functional index (AFI) were evaluated at four- and twelve-week post at each groups. Each groups were randomly sacrificed three rats and observation outward appearance of tendon and growth of collagen at four- and twelve-week. Each group were sacrificed nine rats and test for diameter, breaking strength, tensile stress of tendon at twelve-week post injury. Result: AFI values: Immobilization+exercise group was unable to test to AFI at four-week post injury, so test to AFI was only to control group and exercise group at four-week post injury to used t test, and not significantly between the two groups. The AFI were not significantly between the three groups at twelve-week post injury, but the rats was unable walking to normal by foot of injury limb to immobilization+exercise group, so it was necessary further studies can calculate to more proper of AFI for immobilization+exercise group at twelve-week post injury. Collagen growth: The type III collagen was began to change become type I collagen in three groups at four- and twelve-week post injury, and all group was form crimp to collagen structure. However, the collagen structure was confusion both control group and immobilization+exercise group at four-week post injury, collagen structure was confusion to immobilization+exercise group at twelve-week post injury. Tendon diameter: Not found significantly to normal limbs and injury limbs to tendon diameter between the three groups, but normal limbs were significantly smaller than injury limb to tendon diameter in each groups. Tendon breaking strength: Not found significantly to normal limbs and injury limbs to tendon breaking strength between the three groups, and normal limbs were significantly smaller than injury limbs to tendon breaking strength of control group at twelve-week post injury, and injury limbs were smaller than normal limbs to tendon breaking strength of immobilization+exercise group at twelve-week post injury. Tendon tensile stress: Not found significantly to normal limbs and injury limbs to tendon tensile stress between the three groups, but injury limbs were significantly smaller than normal limb to tendon tensile stress in each groups. Conclusion: Compared to immobilization, the function of Achilles tendon, tissue structure, and mechanic feature are more normal due to the intervention of exercise. However, no obvious benefit for tendon repair was found. As a result, further adjustment for exercise intensity in the latter period of the rehabilitation may lead to normal in tendon tensile stress of Achilles tendon. The period of fixing injured limbs should be shortened due to the negative results from a period of a 4-week of immobilization in the present study. Chang-Bin Yang 楊昌斌 2014 學位論文 ; thesis 81
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description 碩士 === 國立東華大學 === 體育與運動科學系 === 102 === Abstract The aim of this study was to investigate the effect of different treatment model on Achilles tendon rupture recovery on different time in rats. Methods: Forty-five Spraque-Dawley (SD) male rats (eight weeks old) randomly assigned to three groups: control, exercise, immobilization+exercise. Exercise group was exercise intervention at five-day post injury. Immobilization+exercise group was immediately immobilization used cast after injury, and dismantle cast at the same time exercise intervention was began at four-week post injury. The Achilles tendon functional index (AFI) were evaluated at four- and twelve-week post at each groups. Each groups were randomly sacrificed three rats and observation outward appearance of tendon and growth of collagen at four- and twelve-week. Each group were sacrificed nine rats and test for diameter, breaking strength, tensile stress of tendon at twelve-week post injury. Result: AFI values: Immobilization+exercise group was unable to test to AFI at four-week post injury, so test to AFI was only to control group and exercise group at four-week post injury to used t test, and not significantly between the two groups. The AFI were not significantly between the three groups at twelve-week post injury, but the rats was unable walking to normal by foot of injury limb to immobilization+exercise group, so it was necessary further studies can calculate to more proper of AFI for immobilization+exercise group at twelve-week post injury. Collagen growth: The type III collagen was began to change become type I collagen in three groups at four- and twelve-week post injury, and all group was form crimp to collagen structure. However, the collagen structure was confusion both control group and immobilization+exercise group at four-week post injury, collagen structure was confusion to immobilization+exercise group at twelve-week post injury. Tendon diameter: Not found significantly to normal limbs and injury limbs to tendon diameter between the three groups, but normal limbs were significantly smaller than injury limb to tendon diameter in each groups. Tendon breaking strength: Not found significantly to normal limbs and injury limbs to tendon breaking strength between the three groups, and normal limbs were significantly smaller than injury limbs to tendon breaking strength of control group at twelve-week post injury, and injury limbs were smaller than normal limbs to tendon breaking strength of immobilization+exercise group at twelve-week post injury. Tendon tensile stress: Not found significantly to normal limbs and injury limbs to tendon tensile stress between the three groups, but injury limbs were significantly smaller than normal limb to tendon tensile stress in each groups. Conclusion: Compared to immobilization, the function of Achilles tendon, tissue structure, and mechanic feature are more normal due to the intervention of exercise. However, no obvious benefit for tendon repair was found. As a result, further adjustment for exercise intensity in the latter period of the rehabilitation may lead to normal in tendon tensile stress of Achilles tendon. The period of fixing injured limbs should be shortened due to the negative results from a period of a 4-week of immobilization in the present study.
author2 Chang-Bin Yang
author_facet Chang-Bin Yang
Wun-Yi Fang
方文怡
author Wun-Yi Fang
方文怡
spellingShingle Wun-Yi Fang
方文怡
The Effects of Different Treatment Model on Achilles’ Tendon Rupture Recovery.
author_sort Wun-Yi Fang
title The Effects of Different Treatment Model on Achilles’ Tendon Rupture Recovery.
title_short The Effects of Different Treatment Model on Achilles’ Tendon Rupture Recovery.
title_full The Effects of Different Treatment Model on Achilles’ Tendon Rupture Recovery.
title_fullStr The Effects of Different Treatment Model on Achilles’ Tendon Rupture Recovery.
title_full_unstemmed The Effects of Different Treatment Model on Achilles’ Tendon Rupture Recovery.
title_sort effects of different treatment model on achilles’ tendon rupture recovery.
publishDate 2014
url http://ndltd.ncl.edu.tw/handle/ng465f
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