| Summary: | 碩士 === 弘光科技大學 === 化妝品科技研究所 === 103 === This paper describes a novel impedance chip for the detection of emulsion stability and moisturizing efficacy. Each impedance chip contains eight pairs of indium tin oxide microelectrode arrays for detecting eight samples, and six chips can be connected with the switch relay to measure 48 samples in the system simultaneously. The proposed impedance chip has the advantages of needing only a 0.5 mL sample volume, and providing parallel, continuous, and real-time detection. In the experiment of emulsion stability, the results indicated that the phase separation rate was faster in the lower surfactant concentration. The phase separation reaction time for completing the measured phase separation process differed for each of the three methods. The phase separation reaction time was shorter when using the impedance chip method compared to the other two methods. In the experiment of moisturizing efficacy, the effects of the moisturizer concentration on the moisturizing efficacy of a glycerin, hyaluronic acid solutions were studied by mean of a balance, and by impedance chip. A good moisturizing efficacy was demonstrated in the concentrated solutions of moisturizers, either for glycerin or hyaluronic acid. The proposed impedance chip was more sensitive than the balance. Therefore the proposed impedance chip has a quick reaction response to detect emulsion stability and moisturizing efficacy for future applications.
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