| Summary: | 碩士 === 中山醫學大學 === 生物醫學科學學系碩士班 === 102 === In Taiwan, the percentage of myopia has reached as high as 62%. The current control myopia methods include bifocal spectacle lenses, progressive spectacle lenses, soft bifocal contact lenses, biological agents such as atropine and pirenzepine as well as orthokeratology (Ortho-K).Ortho-K provides clear vision despite of not wearing lenses during daytime. The Ortho-K has been proven to be effective in terms of delaying the development of myopia, but the mechanism behind it still awaits further clarification. The purpose of this study is to evaluate the changes of refractive error in the children who were prescribed with Ortho-K, at the same time to seek for the factors that affect the result of Ortho-K wear. By comparing the refractive values before prescribing Ortho-K and the values 6 years after wearing Ortho-K, find the relationship between the two and then determine the factors that lead to retarding myopia progression of Ortho-K wear. This study analyze52 children of age between 12-18 whom were prescribed with Ortho-K for 6 years, where this selected children have myopia of less than -4.00 D and astigmatism of less than -1.50 D. The data are compared between the basic parameters such as gender, age, spherical equivalent refractive, keratometry and corneal eccentricity with the changes in refractive error. The result shows that after prescription, the females of age 12-18 have better myopic control than the males and the higher the refractive error prior to prescription of Ortho-K, the lesser the change in refractive error after prescription. Age, corneal curvature corneal and eccentricity do not affect the changes in refractive error. According to the result, Ortho-K is more related to factors such as gender, age, initial refractive error and corneal curvature.
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