The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents

The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents

碩士 === 中國醫藥大學 === 藥物化學研究所碩士班 === 102 === Various halomethyleniminium salts as novel Vilsmeier reagents were synthesized from the reaction of formamide or N-methylformamide with phosphoryl chloride. Treatment of N-1-substituted-aminopyrazoles including, N-1-(2-pyridinyl)-5-aminopyrazoles and N-1-(2-q...

Full description

Bibliographic Details
Main Authors: Chun-Hsi Chang, 張濬璽
Other Authors: Fung-Fuh Wong
Format: Others
Language:en_US
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/95634777776867134802
id ndltd-TW-102CMCH5549001
record_format oai_dc
spelling ndltd-TW-102CMCH55490012016-03-09T04:30:43Z http://ndltd.ncl.edu.tw/handle/95634777776867134802 The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents 利用新型Vilsmeier–type 試劑化學選擇性合成吡唑[3,4-d]嘧啶， N-1-氫-吡唑-5-甲醯胺和 N-1-氫-吡唑-5-醋酸甲醚類化物之反應性及生物活性之探討 Chun-Hsi Chang 張濬璽 碩士 中國醫藥大學 藥物化學研究所碩士班 102 Various halomethyleniminium salts as novel Vilsmeier reagents were synthesized from the reaction of formamide or N-methylformamide with phosphoryl chloride. Treatment of N-1-substituted-aminopyrazoles including, N-1-(2-pyridinyl)-5-aminopyrazoles and N-1-(2-quinolinyl)-5-aminopyrazoles with these Vilsmeier reagents to obtain the corresponding pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine products. The experimentant results were different with our previous data which the formylated amidylpyazole and formamidine products were obtained under the similar reaction conditions. Fung-Fuh Wong 翁豐富 2013 學位論文 ; thesis 106 en_US
collection NDLTD
language en_US
format Others
sources NDLTD
description 碩士 === 中國醫藥大學 === 藥物化學研究所碩士班 === 102 === Various halomethyleniminium salts as novel Vilsmeier reagents were synthesized from the reaction of formamide or N-methylformamide with phosphoryl chloride. Treatment of N-1-substituted-aminopyrazoles including, N-1-(2-pyridinyl)-5-aminopyrazoles and N-1-(2-quinolinyl)-5-aminopyrazoles with these Vilsmeier reagents to obtain the corresponding pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine products. The experimentant results were different with our previous data which the formylated amidylpyazole and formamidine products were obtained under the similar reaction conditions.
author2 Fung-Fuh Wong
author_facet Fung-Fuh Wong
Chun-Hsi Chang
張濬璽
author Chun-Hsi Chang
張濬璽
spellingShingle Chun-Hsi Chang
張濬璽
The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents
author_sort Chun-Hsi Chang
title The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents
title_short The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents
title_full The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents
title_fullStr The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents
title_full_unstemmed The study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, N-(1H-pyrazol-5-yl)formamide, or N-(1H-pyrazol-5-yl)formamidine derivatives from N-1-Substituted-5-aminopyrazoles with new Vilsmeier-type reagents
title_sort study of selective synthesis and biological activity of pyrazolo[3,4-d]pyrimidine, n-(1h-pyrazol-5-yl)formamide, or n-(1h-pyrazol-5-yl)formamidine derivatives from n-1-substituted-5-aminopyrazoles with new vilsmeier-type reagents
publishDate 2013
url http://ndltd.ncl.edu.tw/handle/95634777776867134802
work_keys_str_mv AT chunhsichang thestudyofselectivesynthesisandbiologicalactivityofpyrazolo34dpyrimidinen1hpyrazol5ylformamideorn1hpyrazol5ylformamidinederivativesfromn1substituted5aminopyrazoleswithnewvilsmeiertypereagents
AT zhāngjùnxǐ thestudyofselectivesynthesisandbiologicalactivityofpyrazolo34dpyrimidinen1hpyrazol5ylformamideorn1hpyrazol5ylformamidinederivativesfromn1substituted5aminopyrazoleswithnewvilsmeiertypereagents
AT chunhsichang lìyòngxīnxíngvilsmeiertypeshìjìhuàxuéxuǎnzéxìnghéchéngbǐzuò34dmìdìngn1qīngbǐzuò5jiǎxīànhén1qīngbǐzuò5cùsuānjiǎmílèihuàwùzhīfǎnyīngxìngjíshēngwùhuóxìngzhītàntǎo
AT zhāngjùnxǐ lìyòngxīnxíngvilsmeiertypeshìjìhuàxuéxuǎnzéxìnghéchéngbǐzuò34dmìdìngn1qīngbǐzuò5jiǎxīànhén1qīngbǐzuò5cùsuānjiǎmílèihuàwùzhīfǎnyīngxìngjíshēngwùhuóxìngzhītàntǎo
AT chunhsichang studyofselectivesynthesisandbiologicalactivityofpyrazolo34dpyrimidinen1hpyrazol5ylformamideorn1hpyrazol5ylformamidinederivativesfromn1substituted5aminopyrazoleswithnewvilsmeiertypereagents
AT zhāngjùnxǐ studyofselectivesynthesisandbiologicalactivityofpyrazolo34dpyrimidinen1hpyrazol5ylformamideorn1hpyrazol5ylformamidinederivativesfromn1substituted5aminopyrazoleswithnewvilsmeiertypereagents
_version_ 1718201272483446784

Similar Items