Investigation of Cognitive Neuromodulation with Functional Connectivity Altering in Hippocampus with Central Thalamic Deep-Brain Stimulation in a Rodent Model
碩士 === 國立陽明大學 === 醫學工程研究所 === 101 === Hippocampus is considered as the main role of memory consolidation. Learning can be completed after memory consolidation. Recent research showed that stimulation in central thalamus (CL) may enhance cognitive function and the effects in hippocampus during learni...
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| Format: | Others |
| Language: | en_US |
| Published: |
2013
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| Online Access: | http://ndltd.ncl.edu.tw/handle/03688011743208307545 |
| Summary: | 碩士 === 國立陽明大學 === 醫學工程研究所 === 101 === Hippocampus is considered as the main role of memory consolidation. Learning can be completed after memory consolidation. Recent research showed that stimulation in central thalamus (CL) may enhance cognitive function and the effects in hippocampus during learning by histology techniques. However, no further research showed the relationship between the two issues. In this study, we hypothesize that the stimulation in CL can enhance the learning behavior and the brain connectivity may change during learning. A behavioral task is designed to verify the influence in learning after electrical stimulation in CL, and an electrophysiological method is implemented to verify the connectivity and causality changes in hippocampus.
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