DESIGN AND FABRICATION MICROFLUIDIC INTEGRATED DEP-QCM FOR SEPARATING X-SPERM AND Y-SPERM

• Main Authors: Chin-Yuan Cheng, 鄭金源
• Other Authors: Chao-Heng Chen
• Format: Others
• Language: zh-TW
• Published: 2013
• Online Access: http://ndltd.ncl.edu.tw/handle/06665147860315024366

碩士 === 大同大學 === 機械工程學系(所) === 101 === In the recent year, MEMS technology have been developed and applied in various kinds of fields, such as optics, power, sensor, bioengineer and etc. However, with the improvement of quality of the life, people want to have better medical treatment. MEMS technology is applied by biotechnology such as separate bio particles to do some things like medical treatment. In this paper, we focus on human genetics to choose different gender for every people requirement. We designed a microchip to affect sperm in microfluidic by the structure、PH value. After separation, we used DEP-QCM structure to detect and measurement all off the experiment controlled value and the QCM frequency value with voltage and frequency from function generator. In this research, we design a corner and changed the PH value to affect the sperm between X-sperm and Y-sperm. We finally made much of the Y-sperm to turn direct by the different PH value with the buffer solution. And then, sperm would been adsorbed on the QCM and detected with frequency to proof the design is true and effective.