The retrospective study to explore the distribution of the non-motor symptoms and the correlation in symptoms and quality of life in different severity stages Parkinson’s patients

• Main Authors: Chih-wei Lee, 李芝緯
• Other Authors: none
• Format: Others
• Language: zh-TW
• Published: 2012
• Online Access: http://ndltd.ncl.edu.tw/handle/55366535526678291610

碩士 === 慈濟大學 === 護理學系碩士班 === 101 === Parkinson’s disease (PD) is a chronic neurological disorder in elder patient. The annual estimated that the number of patients is increase over 3,000 and the growth rate is 4.37% per year in Taiwan. The patients were suffered from the motor symptoms and non-motor symptoms in the Parkinson’s disease (PD) and affect their life of quality. Many studies have demonstrated the relationship between in quality-of-life (HRQL) and motor symptoms in PD. However, there was no study to report the correlation in symptoms and quality of life in PD. The aim of this study was to explore the distribution of the non-motor symptoms in PD and the relationship between in these symptoms and the quality of life status. This is a retrospective study. The cross-sectional study design and chart retrospectively review methods was used in our study. We were enrolled 54 patients with PD (stage I to IV, Hoeha & Ynhr classification) in neurology and neurosurgery wards of the General Hospital in eastern of Taiwan from 2009 to 2011. Self-recording questionnaires was used in this study, include the Mini-mental state examination (MMSE), Beck depression inventory (BDI) and 39-item Parkinson’s disease questionnaires (PDQ-39). The SPSS 19.0 software for Mac will be used for statistical analysis. The results showed that the significant correlation between in neuropsychiatric manifestations, autonomic complications (r = .919，p < .01) and sleep disorders (r = .406，p < .05) with mild severity stages of the Parkinson’s patients. The significant correlations between in the neuropsychatric manifestations and sleep disorders (r = .396，p < .05) with high severity stages of the Parkinson’s patients, and the significant correlations between in the autonomic complications and sleep disorders (r = .520，p < .01) were also observed. The impact of quality-of-life (HRQL) by the non-motor symptoms that the major symptom is autonomic complications, second is neuropsychatric manifestations, and last is sleep disorders. Otherwise, we also found the impact of quality-of-life (HRQL) and depression by disease severity. However, the non-motor symptoms were happened in different severity stages of the Parkinson’s patients. We hope this study can clearly demonstrate the relationship between in PD’s non-motor symptoms and the status of quality-of-life (HRQL). Moreover, we hope to enhance the nurses’ knowledge and increase the education ability to family about the non-motor symptoms in PD patients. Finally, the patients will improve the self-care and life quality.