The Parametric Studies of Micro-Channel Design used in the Cell Separation and Moving

• Main Authors: He-Cian Li, 李和謙
• Other Authors: 林依恩
• Format: Others
• Language: zh-TW
• Published: 2013
• Online Access: http://ndltd.ncl.edu.tw/handle/35zrd2

碩士 === 國立虎尾科技大學 === 機械與機電工程研究所 === 101 === Microfluidic biochips developed by micro-electromechanical systems, biomedical science and technology will be there for a considerable help. In this study, the centrifugal force as the driving force, the use of the fluid analysis software Comsol particle tracking module, analog and observe particles move in a micro-flow channel of the numerical analysis of the situation. By PDMS molds to get the best micro-flow channel geometry, reuse edge sheath flow of hydraulic fluid in the sample stream compression effect, explore the impact of changing the direction of cell movement. From the simulation and experimental results obtained to prove that we have designed a microfluidic chip geometry for Biomedical feasibility, as the flow channel geometry design reference. Since no one had found using particle tracking module to simulate cell migration situation, so we have to try to do the simulation. The cell characteristics and situation is not easy to control, so the simulation and experimental results will be different. PDMS molds can not only reduce costs, but also to make mass production, hope can be used in biomedical related fields.