Studies on the cholesterol reducing effect of rice bran in hyperlipidemia hamsters

• Main Authors: Yu-Dan Cheng, 鄭渝丹
• Other Authors: Tzou-Chi Huang
• Format: Others
• Language: zh-TW
• Published: 2013
• Online Access: http://ndltd.ncl.edu.tw/handle/82008634546844432586

碩士 === 國立屏東科技大學 === 食品科學系所 === 101 === Rice bran is a by-product from paddy during milling to a polished rice. According to the literature, rice bran contain various nutrients and antioxidants that could be effective in preventing cardiovascular disease. The purpose of this study is to investigate of rice bran on the cholesterol reduction effect, the hyperlipidemia hamsters animal model will be used with rice brans. In this study, the hamsters were fed basal diets plus 0.2% added cholesterol and rice bran (2.5%, 7.5% and12.5%, respectively) for 8 weeks. After 56 days, the serum cholesterol was higher in hamsters fed the high-cholesterol diet than the normal group but significantly decreased in rice bran group. Serum high-density lipoprotein cholesterol was lowered in the high-cholesterol diet group but it was significantly increased in hamsters compared with the rice bran group. The serum total cholesterol concentration was significantly lower in all the rice bran group (13.18%, 8.26% and 11.50%), compared to high-cholesterol diet group. The serum triglyceride concentration was significantly lower in all the rice bran group (37.68%, 9.21% and 24.8%), compared to high-cholesterol diet group. Aortic atherosclerosis formation was significantly reduced by rice bran diets compared to the high-cholesterol diets group. These results suggested that the rice bran intake is related with decreased cholesterol absorption and prevent aortic atherosclerosis production.