The Role of SENP1 in OCT4 Protein Stability and Chemotherapeutic Sensitivity of Testicular Embryonal Carcinoma Cells Under Hypoxic Conditions

博士 === 國防醫學院 === 生命科學研究所 === 101 === Testicular germ cell tumors (TGCTs) generally respond well to chemotherapy, but tumors that express low levels of the transcription factor OCT4 are associated with chemoresistance and poor prognosis. Hypoxia is known to induce drug resistance in TGCTs, however, t...

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Bibliographic Details
Main Authors: Wu, Yu-Chih, 吳友志
Other Authors: Shen, Chia-Ning
Format: Others
Language:en_US
Published: 2012
Online Access:http://ndltd.ncl.edu.tw/handle/69551670324971150982