| Summary: | 碩士 === 國防醫學院 === 公共衛生學研究所 === 101 === Chronic kidney disease (CKD) is one of the predominant epidemic diseases in the world.The increasing prevalence and incidence of CKD also meet to the critical problem in medical cost.Because of the stressful environment, aircrews, who have a high risk of renal dysfunction.It would be a better strategy in preventing the CKD from bad to worse is to diagnose in early stage. In order to achieve this objective, we investigate the prevalence of CKD, and establish the predictable model of disease variation.
In this longitudinal study, we elected the 212 Subjects who had participated medical examinations in military hospital since 2004 to 2010, and can be tracked 4 years. By the using aMDRD formula to estimate the glomerular filtration rate, in addition, combine with the NKF-K/DOQI to decide the CKD patients.
In these results, the prevalence of CKD was 3.8%, 9.4%, 9.0%, 9.4% for four years. In logistic regression analysis,unusual urobilinogen, ketone, and normal white blood cells in urine and urinary occult blood positive, will increase the risk of CKD. Urinary occult blood positive can predict future risk of CKD. Moreover, GEE model shows that a higher risk of CKD with the examination time, age and experience seniority has a negative effect. In conclusion abnormal urobilinogen, ketone, and normal white blood cells in urine and urinary occult blood positive, might serves as an independent predictor of CKD.
In the future, we can focus on not only annual physical examine, but also in simple and accurate examination, such as urinary occult blood. To determine the possibility, then prevent the degeneration of CKD in our aircrews.
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