Facile Preparation of Chitosan-Immobilized Magnetic Nanoparticles for Selective Enrichment of Phosphorylated Peptides

碩士 === 國立暨南國際大學 === 應用化學系 === 102 === A facile and effective approach to synthesize chitosan-immobilized magnetic nanoparticles was proposed using carbon-encapsulated iron nanoparticles (Fe@CNPs) as the magnetic core.Poly(acrylic acid)-coated Fe@CNPs were prepared by free radical polymerization of a...

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Bibliographic Details
Main Authors: Peng-Hsuan Tsai, 蔡朋璇
Other Authors: Chih-Che Wu
Format: Others
Language:zh-TW
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/34181588009116319015
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Summary:碩士 === 國立暨南國際大學 === 應用化學系 === 102 === A facile and effective approach to synthesize chitosan-immobilized magnetic nanoparticles was proposed using carbon-encapsulated iron nanoparticles (Fe@CNPs) as the magnetic core.Poly(acrylic acid)-coated Fe@CNPs were prepared by free radical polymerization of acrylic acid and used as magnetic substrates for subsequent Chitosan immobilization.The chitosan-immobilized magnetic probes were applied for rapid and selective identification of phosphopeptides from complex peptide mixtures by MALDI-TOF MS.