Design of Automatic Biochemical Platform

• Main Authors: Hui-YiChen, 陳慧宜
• Other Authors: Chi-Chuan Hwang
• Format: Others
• Language: zh-TW
• Published: 2013
• Online Access: http://ndltd.ncl.edu.tw/handle/55403243671383850191

碩士 === 國立成功大學 === 工程科學系碩博士班 === 101 === In this study, we take the advantage of precision manufacturing techniques combined with biotechnology to construct automated biochemistry platform. In this issue, it is popular in semi-automated platform in the world. In Taiwan, Many organizations have used semi-automated platforms for scientific researches. Amount of errors which were difficult to be corrected while the platform is working and the researchers still need to monitor the platform by themselves nowadays. In order to save the monitoring time of the researchers, we design a full automated biochemistry platform which contains three movable apparatus and two fixed ones, including Change lifts of apparatus, Conversion platform of liquid handling, Conveyer system of microtiter plate, Storage rack of apparatus and working bench. Firstly, we build the components of the platform by using CAD software, then, the models are imported to the simulation software, Webots. Secondly, we set the physical mechanics of the power and the carrier systems and then optimize the best motion of pathways and find out the best physical parameters in our structure. We put the sensors in both ends of the sport pathways and the feedback systems will auto-adjust the minor movement. And we will also build the machine learning in the controlling system. The results show that the designed automated biochemistry platform can achieve high performance with easy operation and high flexibility by simulation. This study provides optimized parameters and apply them to the construction of platform to speeding the building time. This will also lower the cost of biochemical experiments. We hope the automated biochemical platform can help scientists and researchers to decrease repetitive works, speed up their work and have more time to think their projects.