Electrochemical synthesis of advanced functional materials based on electroactive polymers for the electrochemical sensing applications

• Main Authors: Baskar Selvaraj, 巴斯卡
• Other Authors: Jyh-Myng Zen
• Format: Others
• Language: en_US
• Published: 2013
• Online Access: http://ndltd.ncl.edu.tw/handle/91598569846605806720

博士 === 國立中興大學 === 化學系所 === 101 === Polymer-based chemically modified electrodes find widespread applications in diverse fields and are growing consistently than other modified electrodes by fulfilling the current needs and by advancing in faster rate with new developments. This thesis identified the absence of a method to monitor NADH and H2O2 in biological systems involving both of these molecules simultaneously and requirement of a nitrogen and amine rich polymer for the functionalization of carbon surface to prepare nanocomposites. Simultaneous detection method is accomplished using a poly(thionine)-modified preanodized ring-disk screen printed electrode which detects both of the analytes without any interference and a new amine and nitrogen rich functional polymer is developed for the carbon functionalization by converting electrochemically inactive melamine into electroactive polymer on preanodized Screen printed carbon electrode (SPCE*). This new polymer has equal proton/equal electron redox couple and work as biosensor to electrocatalyze s-Nicotinamide adenine dinucleotide reduced disodium salt hydrate (NADH). Amine and nitrogen richness is utilized for the copper and gold nanoparticle preparation where it gives specific structure of Cu spherical nanoclusters and Au nanoflowers respectively by influencing nanoparticle formation through its interaction with metals. Bonded nitrogen of the polymer forms complex with copper which enhance the electrocatalytic activity towards H2O2 with extreme stability under continuous flow of 1 mM H2O2. Free amine present in the Au electrodeposited poly(melamine) modified SPCE* is used for the stable covalent attachment of glucose oxidase (GOx) and achieved DET for the attached enzyme. Finally, multi walled carbon nanotube (MWCNT) is functionalized with the poly(melamine) and decorated Cu and Au nanoparticle where also the polymer gives Cu spherical nanoclusters and Au nanocauliflowers. By using Poly(thionine) polymer modified miniaturized ring-disk electrode, first step is made to develop multi-functional electrode to detect the analytes having detection potential far apart from each other and development of a new polymer poly(melamine) added one more significant advancement to the polymer based chemically modified electrodes.