| Summary: | 碩士 === 高雄醫學大學 === 醫學系神經學科碩士班 === 101 === The definition and existence of Internet addiction disorder (IAD) as psychological disorders is still debated in the medical community. IAD has often been compared to impulse control disorder or substance use disorder which all share high levels of impulsivity. The resolution of its cardinal neurocognitive deficit helps to identify those at risk and develop targeted therapies. The present study aimed to investigate the neurocognitive deficit relating to IAD by using Eriksen flanker task triggered event-related potentials (ERP) and frontal test battery (FAB). This study recruited 16 IAD and 18 mentally and physically healthy participants with mean age of 27 and mean education level of 15. All the participants performed FAB and Eriksen flanker triggered ERP. The error rate, reaction rate, and amplitude and latency of ERPs were analyzed. IAD’s behavioral scores in FAB and flanker task were no different from controls. In comparison to the control, IADs showed reduced frontal error- related negativity (ERN) amplitudes; augmented frontal error-related positivity (Pe) amplitude and a trend toward significantly prolonged Pe latency in error responses. Also, IADs have increased N2 central-frontal amplitude and delayed N2 latency in error responses relative to controls. Moreover, IADs have consistent P300 frontal amplitude reduction and delayed P300 latency in correct responses, error response, congruent stimuli and incongruent stimuli. The present study indicated that IAD partly parallels error processing and response inhibition in substance use disorder regarding impulsivity measured on electrophysiological and behavioral level. Yet concrete conclusions cannot be drawn from the present study on causality. But, poor skill in error processing, working memory, error awareness and inhibition of inappropriate responses underlie patterns observed in certain IAD individuals. IADs might be less sensitive to the negative consequences relating to Internet but still continue their demeanor even in the face of detrimental consequences to their interpersonal relationships, lives, works, school and health.
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