Functional analysis of the Cdc20 Mad2-binding motif: amino acid necessary for activation and sufficient for inhibition of the APC/C
碩士 === 長庚大學 === 生物醫學研究所 === 101 === Cells contain a surveillance mechanism called the “spindle checkpoint” that monitors spindle attachments on kinetochores, and delays the metaphase-anaphase transition to prevent chromosome mis-segregation. The target of spindle checkpoint is Cdc20, which regulates...
Main Authors: | , |
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Format: | Others |
Published: |
2013
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Online Access: | http://ndltd.ncl.edu.tw/handle/17546793229190447881 |