Obatoclax derivatives and copper(II) complex mediates DNA cleavage

碩士 === 國立陽明大學 === 生物藥學研究所 === 100 === Prodigiosin, a natural product, have been reported to mediate DNA damage in cancer cells by coordinating with copper complex. The derivative, Obatoclax, replacing pyrrol ring of prodigiosin to indole ring, has shown anticancer activity by inhibiting protein-prot...

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Bibliographic Details
Main Authors: Jung-Hua Chang, 張容華
Other Authors: Chung-Wai Shiau
Format: Others
Language:zh-TW
Published: 2012
Online Access:http://ndltd.ncl.edu.tw/handle/10786845606189775998