Obatoclax derivatives and copper(II) complex mediates DNA cleavage
碩士 === 國立陽明大學 === 生物藥學研究所 === 100 === Prodigiosin, a natural product, have been reported to mediate DNA damage in cancer cells by coordinating with copper complex. The derivative, Obatoclax, replacing pyrrol ring of prodigiosin to indole ring, has shown anticancer activity by inhibiting protein-prot...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2012
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| Online Access: | http://ndltd.ncl.edu.tw/handle/10786845606189775998 |