Spt4 is Selectively Required for Transcription of Extended Trinucleotide Repeats
博士 === 國立陽明大學 === 生化暨分子生物研究所 === 100 === Huntington’s disease (HD), a neuronal degenerative disorder, is caused by expanded CAG repeats at the 5’ end of Htt gene. The expanded CAG repeats encode a long stretch of polyglutamine (polyQ), which has propensity to induce protein aggregation and results i...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2012
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| Online Access: | http://ndltd.ncl.edu.tw/handle/18616238140828112548 |