Freezing Study of the Prostate Tumor Coverage with Respect to Cryoprobe Locations

• Main Authors: Wei-Luen Dai, 戴偉倫
• Other Authors: Hong-Sen Kou
• Format: Others
• Language: zh-TW
• Published: 2012
• Online Access: http://ndltd.ncl.edu.tw/handle/12562994162630476133

碩士 === 大同大學 === 機械工程學系(所) === 100 === Cryosurgery has been applied on several areas of application, including treatment of cancerous prostate growth, skin cancer, lung cancer, and kidney cancer etc. Choosing the number and localization of cryoprobes is an art held by the cryosurgeon and based on the surgeon’s own experience in the treatment of the cryotherapy. Until now, there is no standard operating procedure for preoperative evaluation. The operation target are, the ice ball generated by the low temperature must totally covered the tumor area to ensure the effectiveness of cryotherapy, and the cryoinjury to the surrounding health tissues must be minimized. In this research, according to actual prostate size two kinds of prostate model are set up. Varying the distance between the center of the ice ball and the prostate model, as well as the most outer size of prostate model and the tip of cryoprobe, respectively. Software ESI-CFD is adopted to simulate the bioheat transfer, and the numerical method to simulate the treatment of prostate cryosurgery. By means of mesh generation technology of the ANSYS ICEM CFD to compute the ice ball coverage of the tumor, the utilization rate and the overlapping rate of the ice ball, respectively. It will be determined the optimal location and the insertion depth of cryoprobes. It is believed that the results from this research can supply valuable data to the clinician for the reference of a real cryosurgery in the future.