| Summary: | 碩士 === 國立臺北科技大學 === 材料及資源工程系研究所 === 100 === Until 2011, cancer already is the top among the ten leading causes death over 28 years in Taiwan. The mortality from cancer is increasing every year. At Biomedicine field that focus on cancer therapies. Reducing side effects, decreasing pain and using effective therapies are the way that we hope for. “Thermotherapy” is the most popular one on cancer therapy. Synthesized with Fe2+ and Pt2+ and used Ca10(PO4)6(OH)2 to replace the Ca2+. By this way to let it got magnetic and have the same effect of Cisplatin. And then we got a Ca10(PO4)6(OH)2 that have composited effective.
The preparation for Ca10(PO4)6(OH)2 used Co-precipitation. During operated Co-precipitation that we add FeCl2．4H2O and K2PtCl4 to change compose of Ca10(PO4)6(OH)2 . Keeping temperature at 80 °C, and pH＝9~9.5. And then used Fourier transform infrared rays spectrometer(FTIR) and X-ray diffraction(XRD) those two machine analyzed its’ composite and characteristic. Scanning electron microscopy (SEM), Energy dispersive spectrometer, and Inductively coupled plasma-optical emission spectrometer (ICP-OES) can helps us analyzed its’ surface and chemical property. Finally used Vibrating sample magnetometer (VSM) analyzed its’ magnetic characteristic.
Researching result show that it can prepare Ca10(PO4)6(OH)2 by using Co-precipitation. And the content of platinum is 0.034, and iron is 0.133. From the cart of Hystersis curve, it can prove the Ca10(PO4)6(OH)2 has magnetic. Commercial high frequency machine offered alternating current to find our magnetic. And then we can know the thermal energy from magnetic hysteresis. During 10 minutes can get the perfect temperature is 43~46°C.
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