The antihyperlipidemic effect on the combination of ethanol extracts of Andrographis paniculata and Acanthopanax Senticosus in hyperlipidemic hamsters

• Main Authors: Fu-Ming Wang, 王富銘
• Other Authors: none
• Format: Others
• Language: zh-TW
• Published: 2012
• Online Access: http://ndltd.ncl.edu.tw/handle/31557358114797322696

碩士 === 大仁科技大學 === 製藥科技研究所 === 100 === The aim of the present study was going to evaluate the plasma lipids lowering effect on the prescription composed of Andrographis paniculata extract and Acanthopanax Senticosus extract at the ratio of 1:3 (APAS). In the present study, the plasma lipid levels were evaluated after hyperlipidemic hamster receiving 8-weeks oral administration with APAS, that was compared with those from LipoCol Forte○R (100 mg/kg/day)-treated group. It has been shown that the plasma lowering activities of APAS (500 mg/kg/day) in TC, TG and LDL-C was approached to 24.34±2.21, 22.94±2.97 and 22.68±2.76％, respectively. The plasma lowering activities of LipoCol Forte (100 mg/kg/day) in TC, TG and LDL-C was nearly to 27.22±3.14, 31.06±2.83 and 26.63±3.12 ％, respectively. The plasma lipids lowering potency of APAS is similar with that produced by LipoCol Forte. The results showed that APAS poses the capacity to ameliorate hyperlipidemia.