Investigating the practicability of using implantable multi-channel neuroprobes to record neuronal activities in rat thalamus

• Main Authors: Chia-Hsin Kuo, 郭家炘
• Other Authors: 趙福杉
• Format: Others
• Language: zh-TW
• Published: 2012
• Online Access: http://ndltd.ncl.edu.tw/handle/13273248836948038183

碩士 === 國立臺灣大學 === 醫學工程學研究所 === 100 === The responses of cerebral neural activities are different in anesthetized and awake states, and their real functions can only be evaluated in conscious state. To achieve this goal, implantable neuroprobes play an important role to record the neural activities in conscious state. There are many commercialized implantable neuroprobes and most of them are designed to record the responses of cerebral cortex, and those for recording in thalamus are deficient. The ventral posterior lateral nuclei convey the somatosensory signals and it also has the property of somatotopic organization. This research establishes the map to the hindlimb in the VPL nuclei and evaluates the effect of the multi-channel neuroprobe, produced by NeuroNexus Technologies. The result shows that the responses decay by days, and the extent are different by different depth of VPL. The neuroprobe could record the signals clearly in at least three months.