| Summary: | 碩士 === 國立臺灣大學 === 生醫電子與資訊學研究所 === 100 === In this research, we develop a multi-processor platform for integration of physiological signals which is implemented on screening newborns for congenital heart disease. The multi-processor platform measures the triple integrated signals, including the phonocardiogram, electrocardiogram (ECG), and pulse oximetry. The built-in diagnostic algorithm provides the management guidelines for practitioners. We take seven critical and significant heart diseases of newborns into account. From the result, the system has high diagnosis rate of congenital heart disease of newborns.
The multi-processor platform is based on TI’s microprocessor MSP430FG439. After the front-end circuit captures the physiological signals, these signals transmit into microprocessor for A/D converting and then transmit to back-end PC by wireless Bluetooth for analyzing the disease characteristics and show the results.
To enhance the quality of heart sound signal, using the TI’s analog chip AIC3254 with mini-DSP technology to implement the noise cancellation adaptive filter and the SNR (signal-to-noise ratio) of the heart sound signal is 21.78 dB. In the part of electrocardiogram, using the TI’s Zero-drift Instrumentation Amplifier INA333 and the SNR of the ECG signal is 12.5 dB. In the part of pulse oximetry, using the firmware code of MSP430FG439 and the Nellcor neonate silicone wrap probe to measure the oxygen saturation.
The system is designed with very simple process. With the system, the newborns need not to be changed consultation for measuring different physiological signal. Furthermore, it doesn’t need the professional doctors and nurses to diagnose and thus it can reduce the cost of traditional screening procedure. Because of the advantages of portability and property of easy manipulation, it will take less than 5 minutes to finish screening. It is not only suited to newborn congenital heart disease screening at the hospital, but can also be used at home. After a baby discharges from the hospital nursery, parents can still use the system to inspect their baby’s situation.
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