以空間統計研究台灣地區肺癌與重金屬之相關性

• Main Author: 陳雯君
• Other Authors: 連怡斌
• Format: Others
• Language: zh-TW
• Published: 2012
• Online Access: http://ndltd.ncl.edu.tw/handle/31605117274020794860

碩士 === 國立彰化師範大學 === 統計資訊研究所 === 100 === In Taiwan, the incidence rate of lung cancer increased year by year over the past decade. Besides, the prognosis is very poor. It is well-known that smoking and secondhand smoke are important risk factors of lung cancer, however the inconsistency between the trends of smoking rate and lung cancer rate reveals the existence of other potential environment risk factors. In this study, spatial statistical methods were used to explore the association between the incidence of lung cancer and some environment indices, including heavy metals concentrations of soil and the deprivation index of livability conditions. Sources of this study are National Cancer Registry database (extracted from the 2002-2008 clinical diagnosis of lung cancer), the database of prevalence health behavior in Taiwan townships, and soil heavy metal content survey in Taiwan. We merged these data and found out that it is presented spatially. Therefore Global spatial autocorrelation, Local spatial autocorrelation and spatial regression techniques were used in order to pick out the factor with significant impact on lung cancer. Our results shows that the incidence rate of lung cancer in Taiwan spatially clustered in west coast of Changhua, Yunlin, Chiayi, and the northern part of Taiwan including Taoyuan, Taipei, Ilan County. The hot spots of male lung cancer incidence rate similar to those described above. the hot spots of female lung cancer incidence rate are in the coastal region of Tainan and Pingtung County. The results from spatial regression models suggest that beside the male smoking prevalence, heavy metal lead (Pb) and arsenic (As), in the environment may also be potential risk factors of lung cancer.