The Effect of Energy Replacement after Exercise on High Fat Meal Induces Immune Response

• Main Authors: Fang-Chiao Chen, 陳芳喬
• Other Authors: 巫錦霖
• Format: Others
• Language: zh-TW
• Published: 2012
• Online Access: http://ndltd.ncl.edu.tw/handle/92rekh

碩士 === 國立中興大學 === 運動與健康管理研究所 === 100 === Chronic low-grade inflammation as a risk for the atherosclerosis and insulin resistance is base on the observation of elevated blood levels of pro-inflammatory cytokines in people with postprandial hyperlipidemia. Studies have shown that a single bout of exercise performed a prior high fat meal reduce postprandial TG and pro-inflammatory cytokines. The energy expended during exercise session appears to be a major determinant of the decrease in postprandial lipemia. The investigation examined the effect of energy replacement after low-intensity aerobic exercise on high fat meal induces immune response. Eight healthy young men completed three treatment in randomized order after three dietary restrictions: rested for 60 min (C), and completed a bout of aerobic exercise at 50% VO2max for 60 min (EX), and provide glucose to replace the energy expended after exercise at 50% VO2max for 60 min (EX+G). Meal and glucose were ingested after exercise at 2h later in EX+G trial. The high fat meal (1.2 g/kg fat, 1.1 g/kg carbohydrates, 0.33 g/kg protein) was ingested on next morning. Blood sample was obtained before the high fat meal was ingested and in the postprandial at 30, 60 , 120, 180, 240, 300 and 360 min. The white blood cell and neutrophil was no changes after high fat meal. lymphocyte was steadying increase from postprandial 60~120 min to 360 min . C-reactive protein was increased at 180 min after high fat meal, there was no significant changes in tumor necrosis factor-α、interleukin -1β、interleukin -6、interleukin -8、interleukin -10 between trials following the high fat meal. In conclusion, energy replacement did not change the high fat meal induced postprandial inflammatory markers.