A study on high strength and low modulus dental Ti-5Cr-9Mo alloy by surface modification

• Main Authors: Hsiao-Yun Huang, 黃曉筠
• Other Authors: Hsueh-Chuan Hsu
• Format: Others
• Language: zh-TW
• Published: 2012
• Online Access: http://ndltd.ncl.edu.tw/handle/14240151932627990940

碩士 === 中臺科技大學 === 醫學工程暨材料研究所 === 100 === In this study, cp Ti and Ti-5Cr-9Mo alloy were used as the substrates. In order to enhance biocompatibility of the substrates, the nanotubes were fabricated by anodic oxidation and the RGD peptides were grafted on the surface. The corrosion resistance of the substrates with a nanotube surface was examined. The results show that the highly ordered nanotube oxide layers developed on the surface of c.p. Ti and Ti-5Cr-9Mo alloy in the 0.3 M NaCl and 0.14 M NH4F mixed solution at an appropriate electric potential for one hour. After being annealed at 450℃ for four hours, the nano-tubes transformed into a rutile crystal structure. The average inner diameter of the nanotubes formed on c.p. Ti was 40 ~ 50 nm, with a tube length of 300 nm. The average inner diameter of the nanotubes formed on Ti-5Cr-9Mo alloy was 40 ~ 50 nm, with a tube length of 250 nm. When testing the corrosion resistance of the nanotubed surface of c.p. Ti and Ti-5Cr-9Mo alloy in Hank''s solution after heat treatment, the corrosion potential (Ecorr) increased and the corrosion current density (Icorr) reduced when compared with untreated specimens. This result shows that specimens with nanotubes can still maintain good corrosion resistance. XPS analysis results showed that the nanotubes on c.p. Ti are composed of TiO2 and on Ti-5Cr-9Mo alloy are composed of TiO2, Cr2O3 and MoO2. FTIR analysis confirmed that the surface of the nanotubed c.p. Ti and Ti-5Cr-9Mo alloy can be successfully grafted with OMP peptide by covalent bonding. Biocompatibility results showed that grafting OMP peptide to nanotubed cp Ti and Ti-5Cr-9Mo alloy produced the best cell growth activity.