| Summary: | 碩士 === 中山醫學大學 === 公共衛生學系碩士班 === 100 === This dissertation can separate two steps in integrant framework. The first step evidences the methodology of sequential method of age-period-cohort (APC) model. The aims try to establish an appropriate methodological procedure to support the application of sequential method. In consequence, this dissertation suggests using mean absolute of percentage error(MAPE) to choice the more accurate one of the two submodels(AP-C and AC-P) and using Akaike information criterion(AIC) to find the parameters in splines function of the best model-fitting.
Second, in order to test the practicability of first step, I apply this methodological procedure in two epidemiological topics, colorectal cancer and cervical cancer. However, the two epidemiological topics have submitted to international journal. Up to now, the manuscript of colorectal cancer has published in international journal of colorectal disease, and another manuscript has under review in BMC public health.
The sequential method is just one of the many methods of APC analysis. Furthermore, the new methods still continuously develop. It means that the technology of APC model still cannot practice in mostly epidemiological topics in existence. Therefore, that will be necessary to reorganize and integrate the presently methods of APC model in subsequent development, or address another new method in the future.
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