The Risk Factors of the Contraindication Medication of Short-Acting Nifedipine in Hypertensive Patients

• Main Authors: Shih Chang Hsu, 許世昌
• Other Authors: 黃光華
• Format: Others
• Language: zh-TW
• Published: 2012
• Online Access: http://ndltd.ncl.edu.tw/handle/24780791184529357758

碩士 === 中國醫藥大學 === 醫務管理學系碩士班 === 100 === Objective: In recent years, many evidence-based clinical had confirmed that should avoid the use of short-acting nifedipine to treat hypertension. Due to an increased risk of myocardial infarction risk, the purpose of this study was to investigate the risk factors of short-acting nifedipine among hypertensive patients in Taiwan. Methods: This study used secondary data analysis, data subscription to the National Institutes of Health from 2006 to 2010 of one million underwriting sample normalized people file (LHID2005,); The study subject were the prescriptions of hypertensive patients. In the study, we used the generalized estimating equation (GEE) model to analysis the factors of nifedipine prescriptions, includes patient, facilities and physicians characteristics. All analysis was conducted by SAS 9.1.3 statistic software. Results: There were 375,202 nifedipine prescriptions among all 4,386,673 hypertension prescriptions. The hypertensive patients using short-acting nifedipine prescriptions, 29,024 prescriptions in 2006 to 17,039 in 2010 decreased by 41.29%, and a declining trend. The risk factors were, such as female patients, patients who above aged 55, 36-55 years old physician and the high urbanization facilities. Conclusions: The hypertensive patients using short-acting nifedipine prescription was a declining trend these years, but still quite severity. The result of this study is expected to have some contributions in establishing the surveillance indicators and providing useful information for policy-makers to enact relevant policies to ensue prescription safety for hypertension patients.