| Summary: | 碩士 === 國立中正大學 === 光機電整合工程研究所 === 100 === Cutaneous T-cell Lymphoma is a rare skin disease. Due to the low probability of its occurrence, non-professional dermatologist clinics could easily be mistaken for psoriasis or atopic dermatitis. Traditional biopsy detection is an invasive process, it not only undermines the organizational structure, and the cost of pathological diagnosis is high and time-consuming. We used multi-spectral imaging technique to get the spectrum of each pixel in the image of these skin diseases, and use of principal component analysis and principal component scores to distinguish between different diseases. Later, we use 4-band LED color difference calculation to find out the best able to gain color LED chromaticity location, its connection with the white spots can be a particular wavelength. By using this wavelength, we designed an enhancing spectrum, and then we can enhance the color difference between normal and lesion area of the CTCL patients more than 10%. It can make medical diagnosis more efficiency and help patients for early treatment.
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