The Imputation Approach for Linear Regression Model under Semi-Competing Risks Data

碩士 === 國立中正大學 === 數學系統計科學研究所 === 101 === In this thesis, we investigate the linear regression analysis on the non-terminal event for semi-competing risks data. Because the non-terminal event time is dependently censored by the terminal event time, it is relatively difficult to estimate the linear re...

Full description

Bibliographic Details
Main Authors: Hsin-Pin Tu, 杜欣頻
Other Authors: Jin-Jian Hsieh
Format: Others
Language:en_US
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/15768485333370467399
Description
Summary:碩士 === 國立中正大學 === 數學系統計科學研究所 === 101 === In this thesis, we investigate the linear regression analysis on the non-terminal event for semi-competing risks data. Because the non-terminal event time is dependently censored by the terminal event time, it is relatively difficult to estimate the linear regression coefficients. We can not make inference on the non-terminal event time without extra assumptions. Thus, we use the Archimedean copula assumptions to specify the dependence between the non-terminal event time and the terminal event time. We use the mean imputation approach and the median imputation approach to impute the unknow non-terminal event time, and then estimate the linear regression parameters by least square estimation method. According to the simulation results, the mean imputation approach and the median imputation approach perform well. Then, we use the mean imputation approach and the median imputation approach to analyze the Bone Marrow Transplant data.