| Summary: | 碩士 === 元培科技大學 === 放射技術研究所 === 99 === This study investigates the correlation between disk degeneration and fatty infiltration of the lumbar multifidus muscles. Results will helpfully serve as a reference for clinical physicians during disk degeneration diagnosis and treatment method selection. Philips 3.0T magnetic resonance imaging (MRI) was employed as the measuring equipment. Techniques, including non-invasive T2 relaxation time map (T2 Map) and diffusion weighted image (DWI), were utilized to quantify and analyze the degeneration level of the intervertebral disks. Additionally, proton magnetic resonance spectroscopy (1H MRS) was performed to analyze variations in the lumbar multifidus muscles. Subjects aged 20 to 50 were divided into two groups, each with 30 participants: an experimental group that expressed complaints regarding lower back pain, and a control group that did not experience lower back pain.
The study results indicated that subjects with lower back pain displayed significantly lower nucleus pulposus T2 values and apparent diffusion coefficients (ADC) than healthy subjects (80.3 vs. 99.2 ms, p < 0.001; 1.72 vs. 2.46 10-3 mm2/s, p < 0.001). However, fat content of lumbar multifidus muscles did not display any significant difference (18.0 % vs. 13.5 %, p = 0.085). The disability index of lower back pain was significantly correlated with the diffusivity of water molecules in the intervertebral disks (r = -0.435, p < 0.01); a significant difference in such correlation was also discovered between sexes (p < 0.05). Aside from influencing factors such as age and the diffusion rate of water molecules in the nucleus pulposus, the level of atrophy in lumbar multifidus muscles was also significantly correlated with disk degeneration (r = -0.423, p < 0.01).
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