Metformin inhibits lung cancer cells proliferation mediated by activation of p53 via ribosome pretein S7-MDM2 interaction
碩士 === 國立陽明大學 === 醫學生物技術暨檢驗學系暨研究所 === 99 === Metformin is an antidiabetic drug for type 2 diabetes. Epidemic studies have revealed that metformin could reduce the risk of cancer in diabetic patients. Recently, many studies have shown that metformin exerted an antitumoral effect both in vitro and in...
Main Authors: | Chun-Ching Kuo, 郭淳靖 |
---|---|
Other Authors: | I-Tsuen Chen |
Format: | Others |
Language: | zh-TW |
Published: |
2011
|
Online Access: | http://ndltd.ncl.edu.tw/handle/18299477905937555751 |
Similar Items
-
Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating cells in vivo
by: Francoz, Sarah S
Published: (2006) -
Regulation of the MDM2-p53 pathway by the ribosomal protein L7 in response to actinomycin D-induced ribosomal biogenesis stress
by: Tung-Ching, Ho, et al.
Published: (2015) -
Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo
by: Francoz, Sarah
Published: (2006) -
Involvement of the Human Ribosomal Protein L7 in MDM2-p53 pathway upon Ribosomal Biogenesis Stress in A549 Lung Cancer Cells
by: Mu-Fan Chiu, et al.
Published: (2014) -
Re-thinking the role of ribosomal proteins in the Mdm2-p53 axis
by: Daftuar, Lilyn
Published: (2013)