Studies on the inhibitory mechanism of new terpyridine platinum(II) complexes toward mammalian topoisomerases, human thioredoxin reductase 1 and cysteine proteases
博士 === 國立陽明大學 === 藥理學研究所 === 99 === Terpyridine platinum(II) (TP-Pt(II)) complexes are known to possess DNA-intercalating activity and have been regarded as potential antitumor agents. However, their cytotoxic mechanism remains unclear. To investigate the possible mechanism, a series of TP-Pt(II) co...
| Main Authors: | , |
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| Format: | Others |
| Language: | en_US |
| Published: |
2011
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| Online Access: | http://ndltd.ncl.edu.tw/handle/57002084508256200293 |