The Positive Rate and Severity Score for Allergen-Specific IgE Antibodies in Taipei Metropolitan Area

• Main Authors: Shan-fan Chow, 周尚芳
• Other Authors: Prof.Dey-chyi Sheu
• Format: Others
• Language: zh-TW
• Published: 2011
• Online Access: http://ndltd.ncl.edu.tw/handle/65710884129016866496

碩士 === 大同大學 === 生物工程學系(所) === 99 === A sensitive assay of allergen-specific IgE antibodies was important to identify the patient’s allergens. Some reports revealed the prevalence of allergens in Taiwan. The aim of this study was to elucidate the positive rate and severity score of inhalant, food, plant and fungal allergens in patients with the allergic syndromes in Taipei metropolitan area. We collected serum samples from 283 patients. The serum samples were measured by RIDA allergy screen system which determined the allergen-specific IgE antibodies. In conclusions, this study had shown that gender made no difference. But the prevalence of allergens was different from the childhood, adolescent, and adult groups. Sensitized to Dermatophagoides pteronyssinus and Dermatophagoides farina in three age stages showed a highly positive rate and severity score, especially in the adolescent stage. There were 90.2% who patients showed polysensitization against over 2 kinds of allergens. Polysensitization appeared to be common with 2-5 kinds of allergens. D. pteronyssinus was frequently associated with polysensitization to D. farinae and house dust. The results indicated that mites, house dust and foods were the major sensitizing allergens in this study were similar to those in Taiwan and other western countries.