Molecular docking combined with a consensus scoring function to predict protein-ligand affinity and ligand-based pharmacophore search for new drug scaffolds: an application for acetylcholinesterase inhibition

碩士 === 國立臺北科技大學 === 生物科技研究所 === 99 === Alzheimer’s disease is the most common cause of dementia characterized by progressive cognitive impairment in the elderly. It is a chronic, slowly progressive neurodegenerative disorder. The gradual loss of memory, decline in other cognitive functions, and decr...

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Bibliographic Details
Main Authors: Shin-Hua lu, 呂欣樺
Other Authors: 劉宣良
Format: Others
Language:en_US
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/rhr4xr