Structure-activity Relationships of NF-κB inhibitors-IMD-0354 and its derivatives

Structure-activity Relationships of NF-κB inhibitors-IMD-0354 and its derivatives

碩士 === 東海大學 === 化學系 === 99 === Nuclear factor kappa B is a transcription factor of eukaryote, which regulates cell proliferation gene and anti-apoptosis genes. Activated NF-κB causes these genes to over-express and result in cancer, therefore is an attractive target in cancer therapy. We took IMD-03...

Full description

Bibliographic Details
Main Authors:	Li , Yi-rong, 李宜蓉
Other Authors:	Wu , Yu Shan
Format:	Others
Language:	zh-TW
Published:	2011
Online Access:	http://ndltd.ncl.edu.tw/handle/78918131524056338597

Similar Items

Synthesis and Structure-activity relationships of IMD-0354 derivatives as NF-κB inhibitors.
by: Pei-Rong Ou, et al.
Published: (2010)

Studies on the synthesis of IMD-0354 derivatives and their inhibition to transcription factor NF-κB.
by: Hsieh, Onde, et al.
Published: (2011)

Synthesis of IMD-0354 analogs and their inhibition on TNF-α induced NF-κB activation
by: Lo, Jen-Chih, et al.
Published: (2010)

The NF-κB Inhibitor, IMD-0354, Affects Immune Gene Expression, Bacterial Microbiota and Trypanosoma cruzi Infection in Rhodnius prolixus Midgut
by: Cecilia S. Vieira, et al.
Published: (2018-08-01)

Synthesis of Water-soluble IMD-0354 Derivatives and Evaluating Their IKKβ Inhibition
by: Wu, Han-Wei, et al.
Published: (2013)

New Antimicrobial Bioactivity against Multidrug-Resistant Gram-Positive Bacteria of Kinase Inhibitor IMD0354
by: Iliana E. Escobar, et al.
Published: (2020-10-01)

IKKβ Inhibitor IMD-0354 Attenuates Radiation Damage in Whole-body X-Irradiated Mice
by: Kengo Waga, et al.
Published: (2019-01-01)

Studies on the treatment of melanoma with folate acid conjugated dextran and lauryl alcohol loaded with IMD0354
by: Liu C, et al.
Published: (2019-06-01)

IMD-0354 targets breast cancer stem cells: a novel approach for an adjuvant to chemotherapy to prevent multidrug resistance in a murine model.
by: Azucena Gomez-Cabrero, et al.
Published: (2013-01-01)

Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling.
by: Berra Erkosar, et al.
Published: (2014-01-01)

Correction: Microbiota Modulates Host Metabolic Gene Expression via IMD/NF-κB Signaling.
Published: (2014-01-01)

Correction: Drosophila Microbiota Modulates Host Metabolic Gene Expression via IMD/NF-κB Signaling
by: The Staff
Published: (2014-01-01)

Synthesis and structure–activity relationship of benzamides and indoles as NF-κB inhibitors
by: Huang, Chih-Yuan, et al.
Published: (2010)

Imd pathway-specific immune assays reveal NF-κB stimulation by viral RNA PAMPs in Aedes aegypti Aag2 cells.
by: Tiffany A Russell, et al.
Published: (2021-02-01)

Synthesis of M4891-3155 Analogs as NF-κB Inhibitors and Establishing Their Structure-Activity Relationships.
by: HUANG,JYUN-YAN, et al.
Published: (2013)

Comparison of the Potency of Pterostilbene with NF-κB Inhibitors in Platelet Activation: Mutual Activation by Akt-NF-κB Signaling in Human Platelets
by: Chih-Wei Hsia, et al.
Published: (2021-07-01)

Understanding two inhibitors of NF-κB: A20 and IκBβ
by: De, Arnab
Published: (2014)

Simultaneous Suppression of IMD3 and IMD5 in Space TWT by IMD3 and 2HD Signal Injection
by: Dongming Zhao, et al.
Published: (2017-01-01)

NF-κB inhibitors in treatment and prevention of lung cancer
by: Rajan Radha Rasmi, et al.
Published: (2020-10-01)

New quinazoline analogues as NF-κB activation inhibitors
by: Xu, Lu
Published: (2013)

Vaccinia virus protein B14, an inhibitor of NF-κB activation, and its counterpart in MVA
by: McCoy, Laura Ellen
Published: (2010)

Polymorphisms in NF-κB Inhibitors and Risk of Epithelial Ovarian Cancer
by: Kelemen Linda E, et al.
Published: (2009-06-01)

Hepatic NF‐κB‐Inducing Kinase and Inhibitor of NF‐κB Kinase Subunit α Promote Liver Oxidative Stress, Ferroptosis, and Liver Injury
by: Xiao Zhong, et al.
Published: (2021-10-01)

NF-κB and Its Regulators During Pregnancy
by: Fernando Gómez-Chávez, et al.
Published: (2021-05-01)

NF-κB and Its Role in Checkpoint Control
by: Annika C. Betzler, et al.
Published: (2020-05-01)

Myeloid Derived NFκB Regulation of LPS-Induced Endotoxic Shock
by: Tsai, Yi-Ting
Published: (2013)

New sulfurated derivatives of cinnamic acids and rosmaricine as inhibitors of STAT3 and NF-κB transcription factors
by: Elena Gabriele, et al.
Published: (2017-01-01)

Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer
by: Allyson G. McLoed, et al.
Published: (2016-06-01)

NF-κB and Disease
by: Paola Poma
Published: (2020-12-01)

NF-κB Members Left Home: NF-κB-Independent Roles in Cancer
by: Carlota Colomer, et al.
Published: (2017-05-01)

Utilization of IκB–EGFP Chimeric Gene as an Indicator to Identify Microbial Metabolites with NF-κB Inhibitor Activity
by: Lin Yu-Ling, et al.
Published: (2010-10-01)

NFκB inhibitors as a potential novel hypothesized treatment for psoriasis
by: Nima Derakhshan

Differential regulation of NF-κB activation and function by topoisomerase II inhibitors
by: Perkins Neil D, et al.
Published: (2006-04-01)

The NF-κB Inhibitor Curcumin Blocks Sepsis-Induced Muscle Proteolysis
by: Vitaliy Poylin, et al.
Published: (2008-01-01)

Response and Resistance to NF-κB Inhibitors in Mouse Models of Lung Adenocarcinoma
by: Xue, Wen, et al.
Published: (2011)

Synthesis and Identification of Novel Berberine Derivatives as Potent Inhibitors against TNF-α-Induced NF-κB Activation
by: Yan-Xiang Wang, et al.
Published: (2017-07-01)

NFκB and Kidney Injury
by: Ning Song, et al.
Published: (2019-04-01)

NF-κB in Hematological Malignancies
by: Véronique Imbert, et al.
Published: (2017-05-01)

Hypoxia Induced NF-κB
by: Laura D’Ignazio, et al.
Published: (2016-03-01)

Regulation of NF-κB by Calmodulin
by: Antonsson, Åsa
Published: (2003)

Cannot write session to /tmp/vufind_sessions/sess_0tf151rcr8m61m7i4hvj94edmt