The study of optical imaging technique on biological tissues
碩士 === 國立臺灣師範大學 === 光電科技研究所 === 99 === Optical imaging technique has the advantages of cost-effectiveness, non-invasive, rapid imaging and portability. In this thesis, we have two topics. Firstly, we developed a spectral-domain optical coherence tomography system to obtain biological tissue scatteri...
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| Format: | Others |
| Language: | zh-TW |
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2011
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| Online Access: | http://ndltd.ncl.edu.tw/handle/73409820781914967540 |
| Summary: | 碩士 === 國立臺灣師範大學 === 光電科技研究所 === 99 === Optical imaging technique has the advantages of cost-effectiveness, non-invasive, rapid imaging and portability.
In this thesis, we have two topics. Firstly, we developed a spectral-domain optical coherence tomography system to obtain biological tissue scattering, the system uses coherence gating of backscattered light for tomographic imaing of tissue structure. Variation in tissue scattering due to in-homogeneities in the optical index of refraction provide imaing contrast.
Finally, we have successfully used Doppler optical micro-angiography (DOMAG) to image phantom flow and skin blood perfusion in mice. We then conduct in vivo experiments on a mouse brain to demonstrate that DOMAG is capable of quantifying the blood flow within cerebrovascular network.
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