Predicting ABCG2 Inhibitor Binding Affinity Using Pharmacophore Ensemble/Support Vector Machine

碩士 === 國立東華大學 === 化學系 === 99 === ABCG2 (BCRP) is an ATP-dependent membrane transporter that plays a pivotal role in eliminating xenobiotics by active extrusion of xenobiotics from the cell. Because of this phenomenon which results in ABCG2 repels a variety of drugs and hence the resulting in increa...

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Bibliographic Details
Main Authors: Ming-Keng Chiang, 江銘耿
Other Authors: MK Leong
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/23232490754898853810