Two-dimensional Electric-field Simulation for Effect of Electrode Geometry on Sensitivity of Impedimetric Biosensor

碩士 === 國立中央大學 === 電機工程研究所碩士在職專班 === 99 === This research studied five different designs of electrode-pair geometry for impedimetric biosensing applications. These included interdigitated, rectangular, circular, triangular, and dish electrode pairs. ADS (Advanced Design System) software was utilized ...

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Bibliographic Details
Main Authors: Chih-chung Chiu, 邱治中
Other Authors: Jang-zern Tsai
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/96382946856842360953
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Summary:碩士 === 國立中央大學 === 電機工程研究所碩士在職專班 === 99 === This research studied five different designs of electrode-pair geometry for impedimetric biosensing applications. These included interdigitated, rectangular, circular, triangular, and dish electrode pairs. ADS (Advanced Design System) software was utilized to simulate these different electrode-pair designs on their impedance, capacitance, and electric intensity. The simulated capacitances of these five electrode-pair geometries of commensurate dimensions were 1.600 × 10-14 F, 1.086 × 10-14 F, 6.513 × 10-15 F, 6.576 × 10-15 F, 9.924 × 10-15 F, respectively. One of the simulations showed that the electric intensity in the area-of-interest in the interdigitated electrode pair was quasi-uniform. A sensor of this geometry will be insensitive to the movement of the measured object. An impedance change of merely 0.19% was caused by changing location of the measured object. The electric intensity in the area-of-interest in the triangular electrode pair was non-uniform. A sensor of this geometry will be able to sense the movement of the measured object. An impedance change of up to 4.54% was caused by changing the location of the measured object. Among the five electrode-pair types, the interdigitated one had the highest sensitivity. Adding measured substance caused 60.43% impedance change from the status with background solution only. The results of this study will be useful for guiding the electrode-pair geometry design of  impedimetric biosensors.